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The former, often eponymously known as the "Krebs cycle", is the sequence of metabolic reactions that allows cells of oxygen-respiring organisms to obtain far more ATP from the food they consume than anaerobic processes such as glycolysis can supply; and its discovery earned Krebs a Nobel Prize in Physiology or Medicine in 1953.
In energy metabolism, glucose is the most important source of energy in all organisms. Glucose for metabolism is stored as a polymer, in plants mainly as amylose and amylopectin, and in animals as glycogen. Glucose circulates in the blood of animals as blood sugar.
Glucose (blood sugar) is distributed to cells in the tissues, where it is broken down via cellular respiration, or stored as glycogen. [3] [4] In cellular (aerobic) respiration, glucose and oxygen are metabolized to release energy, with carbon dioxide and water as endproducts. [2] [4]
17 lip 2023 · Glucose is central to energy consumption. Carbohydrates and proteins ultimately break down into glucose, which then serves as the primary metabolic fuel of mammals and the universal fuel of the fetus. Fatty acids are metabolized to ketones. Ketones cannot be used in gluconeogenesis.
Beginning in the 1920s, Carl and Gerty Cori conducted a series of pioneering studies that led to our current understanding of the metabolism of sugars. They elucidated the "Cori cycle," the process by which the body reversibly converts glucose and glycogen, the polymeric storage form of this sugar.
17 lip 2023 · Glucose is central to energy consumption. Carbohydrates and proteins ultimately break down into glucose, which then serves as the primary metabolic fuel of mammals and the universal fuel of the fetus. Fatty acids are metabolized to ketones.
30 kwi 2024 · Glucose metabolism is intricately regulated to meet cell energy demands while preventing hyperglycemia or hypoglycemia. The dysregulation of glucose homeostasis underlies the pathogenesis of several metabolic disorders, posing significant health challenges worldwide.
