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5 lut 2010 · The severity of acute kidney injury has a significant effect on the diuretic response to furosemide; a good ‘urinary response’ may be considered as a ‘proxy’ for having some residual renal function.
Furosemide causes greater loss of water than sodium loss, resulting in the production of hypotonic urine. Loop diuretics also cause increased urinary excretion of potassium, calcium, and magnesium by inhibiting the passive reabsorption of these ions.
Furosemide, a potent loop diuretic, is frequently used in different stages of acute kidney injury, but its clinical roles remain uncertain. This review summarises the pharmacology of furosemide, its potential uses and side effects, and the evidence of its efficacy.
24 lip 2019 · Go to: Acute kidney injury (AKI) constitutes a serious clinical hazard in critically ill patients. There are multiple acknowledged risk factors for AKI which can be found in the intensive care unit (ICU) setting, including sepsis, circulatory shock, trauma, and use of nephrotoxic drugs [1].
24 lip 2019 · Furosemide administration has neither an impact on mortality nor the requirement for RRT. Patients at risk of CIN may benefit from furosemide administration. Further well-designed RCTs are needed to verify these findings. Introduction. Acute kidney injury (AKI) constitutes a serious clinical hazard in critically ill patients.
2 wrz 2023 · Subgroup analysis revealed a synergistic effect of furosemide with surgical operation, previous treatment with β-blockers, ACEI/ARB and antibiotics, leading to an increased risk of AKI when used in combination.
4 mar 2020 · Some studies found that furosemide exhibited neutral or deleterious effects in AKI treatment [2, 3, 4]. In contrast, several studies have suggested that furosemide might reduce the need for renal replacement therapy (RRT) and attenuate the severity of AKI [5, 6].
