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3 lis 2020 · While focusing on restoring heart muscle and replenishing lost coronary vessels is clearly important, mounting evidence suggests that achieving full regeneration will require fibroblast, immune, conductive, and nervous cell contributions to the regenerative process.
6 kwi 2023 · In the present study, we defined the cellular and transcriptional landscape of cardiac recovery using snRNA-seq. We compared non-diseased donor controls to patients with HF who experienced...
2 lut 2021 · Recent studies have shown that multiple types of cells within the heart can respond to injury with the activation of distinct signaling pathways. Determining the specific contributions of each cell type is essential for our understanding of the regeneration network organization throughout the heart.
14 maj 2024 · Gao, L. et al. Large cardiac muscle patches engineered from human induced-pluripotent stem cell-derived cardiac cells improve recovery from myocardial infarction in swine.
21 wrz 2017 · This Review summarizes the latest findings on heart reverse remodelling, which demonstrate that despite apparent normalization of function, the molecular changes associated with heart failure...
6 kwi 2021 · The conditional ablation of ERBB2 in embryonic or neonatal mouse CMs leads to reduced proliferation. Consistently, genetic activation of ERBB2 significantly improves cardiac function post-MI, indicating that this pathway can be exploited as a viable target for heart regeneration (D'Uva et al. 2015).
24 sie 2022 · SeisWind® 3D is an evolution of Fugro’s UUHR seismic service that consists of eight solid custom specification digital streamers, with proprietary sources and decimetre accuracy in-sea positioning systems.
