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4 dni temu · FHL2 (Four-and-a-half LIM domain protein 2) is a crucial factor involved in cardiac morphogenesis, the process by which the heart develops its complex structure. It is expressed in various tissues during embryonic development, including the developing heart, and has been shown to play important roles in cell proliferation, differentiation, and migration. FHL2 interacts with multiple proteins ...
25 cze 2020 · Coronary vessels require perivascular support, with arteries surrounded by multiple layers of smooth muscle, whereas capillaries are in direct contact with individual pericytes.
Calcium transients, required to trigger contraction, can be detected even earlier, prior to contraction. In this review, we outline what is currently known about how this early contractile function is initiated and the impact early contractile function has on cardiac development.
9 gru 2008 · The keynote to understanding cardiac function is recognizing the underlying architecture responsible for the contractile mechanisms that produce the narrowing, shortening, lengthening, widening, and twisting disclosed by echocardiographic and magnetic resonance technology.
3 lis 2020 · In this review, we focus on the roles of fibroblasts, immune, conduction system, and nervous system cell populations during heart development and we consider the latest evidence supporting a function for these diverse lineages in contributing to regeneration following heart injury.
30 sty 2020 · EPDCs (Epicardium-derived progenitor cells) emerge from the fetal epicardium through the process of epithelial-to-mesenchymal transition (EMT) and contribute to various cardiac lineages, such as cardiac fibroblasts (CFs), smooth muscle cells (SMCs), and pericytes (PCs).
The aim of this study was to review the diverse progenitor cells of VSMCs and reveal the roles of the diverse progenitor cells in cardiovascular development, abnormal vascular smooth muscle development, and the associated cardiovascular malformations.
