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13 lip 2022 · Viral infections and cardiovascular disease (CVD) share a two-way connection: viral infection can raise CVD risk, and people with CVD are more prone to severe viral infection.
23 lis 2022 · Studies focusing on patients presenting cardiomyopathic symptoms showed that parvovirus B19, adenovirus, CVB3, Epstein–Barr virus, human cytomegalovirus and human herpesvirus 6 are primarily detected in heart samples exhibiting signs of infection (Figure 2).
8 sie 2021 · MyD88 Signaling Leads to Cell Specific Functions in Cardiovascular Disease. Alarmins are recognized by TLRs and cytokine receptors, leading to activation of MyD88 and a subsequent immune response, along with cell specific functions (right panel). The MyD88 independent pathway contributes in parallel.
14 mar 2018 · Infectious myocarditis is the result of an immune response to a microbial infection of the heart. The blood vessels of the heart, both the intramyocardial microvasculature and the large epicardial coronary arteries, play an important role in the pathogenesis of infectious myocarditis.
12 lip 2021 · The expression pattern and potential functions of SARS-CoV-2 binding receptors and the attributes of SARS-CoV-2 virus tropism in a physio-pathological state of heart and blood vessel are precisely described. Of note, the atheroprotective role of ACE2 receptors is reviewed.
24 lut 2021 · Importantly, SARS-CoV-2's ability to infect endothelium is shared by many emerging viruses, including henipaviruses, hantavirus, and highly pathogenic avian influenza virus, all specifically targeting endothelial cells.
31 sie 2010 · As secretory cells, cardiac myocytes are the source of multiple paracrine signals that can affect the coronary vasculature. Some of these—ET-1, FGF2, urocortin, adenosine, and the enzyme heme oxygenase, to name a few—regulate the vascular tone coordinating myocardial requirements for oxygen and nutrients with the blood flow.
