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19 kwi 2022 · Advances in molecular imaging now make it possible to non-invasively visualize the cardiac cellular landscape in humans, providing a means to guide precision therapies.
24 wrz 2020 · Single-cell and single-nucleus RNA sequencing are used to construct a cellular atlas of the human heart that will aid further research into cardiac physiology and disease. Cardiovascular...
13 lis 2017 · Here, we determine the healthy human heart proteome by measuring 16 anatomical regions and three major cardiac cell types by high-resolution mass spectrometry-based proteomics.
24 sie 2022 · SeisWind® 3D is an evolution of Fugro’s UUHR seismic service that consists of eight solid custom specification digital streamers, with proprietary sources and decimetre accuracy in-sea positioning systems.
14 wrz 2021 · Human heart (patho)physiology is now widely studied using human pluripotent stem cells, but the immaturity of derivative cardiomyocytes has largely limited disease modeling to conditions associated with mutations in cardiac ion channel genes.
23 sie 2021 · This Review provides an overview of the current three main approaches for modeling heart physiology and disease in vitro: cardiac specification models, engineered heart tissues/organoids and self-organizing embryonic and cardiac-specific organoids.
1 sie 2004 · Introducing these changes into cardiac cell models succeeds in reproducing failure of repolarization and multiple reexcitations of the kind that generate major arrhythmia and in showing that the major factor involved is the changes in calcium balance.