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1 kwi 2009 · Many ion channels function as part of macromolecular complexes in which many components are assembled at specific sites within the membrane. This review describes the generation of the normal cardiac action potential. The properties of the major ionic currents are the examined in detail.
24 wrz 2020 · Single-cell and single-nucleus RNA sequencing are used to construct a cellular atlas of the human heart that will aid further research into cardiac physiology and disease.
Understanding the mechanisms through which extracellular stimuli modify the functions of cells in the heart and vascular wall gives valuable insights into how perturbations of signalling systems can cause pathological situations.
24 sie 2022 · SeisWind® 3D is designed to offer an efficient data acquisition footprint with the highest resolution to enable detailed ground modelling and interpretation of near surface geology for the safe development of offshore projects.
Identify and describe the components of the conducting system that distributes electrical impulses through the heart. Compare the effect of ion movement on membrane potential of cardiac conductive and contractile cells. Relate characteristics of an electrocardiogram to events in the cardiac cycle.
A comprehensive analysis of cell generation and turnover in the human heart demonstrates that cardiomyocyte numbers are constant throughout the human lifespan, with a low turnover rate. Endothelial and mesenchymal cells are exchanged at a high rate, and their numbers increase into adulthood.
22 cze 2011 · The transverse tubules (t-tubules) are invaginations of the cell membrane rich in several ion channels and other proteins devoted to the critical task of excitation–contraction coupling in cardiac muscle cells (cardiomyocytes).
