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Ketone-prone diabetes or Flatbush diabetes is being increasingly recognized worldwide. It is typically seen in obese middle-aged men with a family history of Type 2 DM. Atypicality in the onset of age and gender variation is increasingly observed ...
In 2002, Sobngwi et al. introduced the term “ketosis-prone diabetes” in a review of diabetes in West Africans. Ketosis-prone diabetes, also known as “Flatbush Diabetes”, has pathophysiology close to that of T2DM but initially exhibits signs and symptoms of T1DM ( 4 ).
1 sty 2018 · is a widespread, emerging, heterogeneous syndrome characterised by patients who present with diabetic ketoacidosis (DKA) or unprovoked ketosis with hyperglycaemia but do not necessarily have the typical phenotype of autoimmune type 1 diabetes.
2 paź 2018 · Major questions remain as to its pathogenesis and whether it is a unique type of diabetes or a subset of more severe type 2 diabetes with greater loss of insulin action in target tissues. This review summarizes the main clinical and mechanistic studies to improve the understanding of ketosis-prone (Flatbush) diabetes.
15 paź 2019 · Ketosis-prone type 2 diabetes (“Flatbush diabetes”) carries features of both classical type 1 and type 2 diabetes and is highly prevalent in African populations.
2 paź 2018 · This review summarizes the main clinical and mechanistic studies to improve the understanding of ketosis-prone (Flatbush) diabetes. Recent findings: Little data are available on the magnitude of KPD in the different susceptible populations.
The term “Flatbush” Diabetes was first applied to the African Americans residing in the ethnically diverse, Brooklyn, New York neighborhood of Flatbush, who presented in DKA at the time of their diabetes diagnosis. While presenting in DKA, these patients ultimately experience a clinical course resembling type 2 diabetes (T2DM).
