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Ketone-prone diabetes or Flatbush diabetes is being increasingly recognized worldwide. It is typically seen in obese middle-aged men with a family history of Type 2 DM. Atypicality in the onset of age and gender variation is increasingly observed worldwide.
Patients with ketosis-prone type 2 diabetes usually present with new-onset severe hyperglycemia and ketosis or diabetic ketoacidosis. The treatment is the same as diabetic ketoacidosis, which requires insulin, intravenous fluid, and electrolyte replacement.
2 paź 2018 · The diabetes is newly diagnosed in these patients at the time of their admission to the hospital for insulin treatment. The inability of glucose to stimulate insulin secretion appears to be the central abnormality leading to the severe hyperglycemia with or without ketoacidosis and persists for several days to weeks despite normalization of the ...
24 sty 2022 · Flatbush diabetes is a mosaicism of clinical manifestations that goes by several names: Flatbush diabetes, ketosis-prone diabetes (KPD), type 1.5 diabetes, or atypical diabetes . While it goes by many different names, this new form of diabetes appears to be increasingly documented all around the world in the last several decades yet remains ...
22 sie 2023 · The goal of new classification schemes is to enable clinicians to predict which patients with diabetic ketoacidosis (DKA) require temporary insulin treatment versus life-long insulin therapy. They also highlight subgroups for genetic and pathogenetic studies.
Ketosis-prone type 2 DM typically presents with diabetic ketoacidosis in patients who fit neither the category of type 1 or type 2 diabetes. Further subcategorization of diabetes is necessary to identify the type and predict outcome and treatment strategies.
In 2002, Sobngwi et al. introduced the term “ketosis-prone diabetes” in a review of diabetes in West Africans. Ketosis-prone diabetes, also known as “Flatbush Diabetes”, has pathophysiology close to that of T2DM but initially exhibits signs and symptoms of T1DM .
