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Flatbush diabetes is a mosaicism of clinical manifestations that goes by several names: Flatbush diabetes, ketosis-prone diabetes (KPD), type 1.5 diabetes, or atypical diabetes . While it goes by many different names, this new form of diabetes appears to be increasingly documented all around the world in the last several decades yet remains ...
24 sty 2022 · Our report sheds light on the atypicality of presentation and summarizes the main diagnostic features of this rare form of diabetes. Increased awareness of this entity can facilitate early diagnosis and management.
24 sty 2022 · Flatbush diabetes is a mosaicism of clinical manifestations that goes by several names: Flatbush diabetes, ketosis-prone diabetes (KPD), type 1.5 diabetes, or atypical diabetes .
2 paź 2018 · Major questions remain as to its pathogenesis and whether it is a unique type of diabetes or a subset of more severe type 2 diabetes with greater loss of insulin action in target tissues. This review summarizes the main clinical and mechanistic studies to improve the understanding of ketosis-prone (Flatbush) diabetes.
22 sie 2023 · The goal of new classification schemes is to enable clinicians to predict which patients with diabetic ketoacidosis (DKA) require temporary insulin treatment versus life-long insulin therapy. They also highlight subgroups for genetic and pathogenetic studies.
Ketosis-prone diabetes, also known as “Flatbush Diabetes”, has pathophysiology close to that of T2DM but initially exhibits signs and symptoms of T1DM . Patients with KPD frequently present with elevated levels of glucose of 500 -700 mg/dL, high levels of ketone, and hemoglobin A 1 C ranging from 12% to 14%.
The absence of autoimmunity, lack of beta-cell dysfunction, and unprovoked ketoacidosis are key attributes in KPD, an emerging form of diabetes mellitus [2-5]. Interestingly, whether KPD is a unique type or a subtype of type 2 diabetes is still considered a topic of debate and needs further study.
