Search results
Ketone-prone diabetes or Flatbush diabetes is being increasingly recognized worldwide. It is typically seen in obese middle-aged men with a family history of Type 2 DM. Atypicality in the onset of age and gender variation is increasingly observed worldwide.
- Ketosis-Prone Type 2 Diabetes (Flatbush Diabetes) in Remission: A ...
Patients with ketosis-prone type 2 diabetes usually present...
- Ketosis-Prone Type 2 Diabetes (Flatbush Diabetes) in Remission: A ...
1 lip 2009 · This variant of diabetes has been referred to in the literature as idiopathic type 1 diabetes, atypical diabetes, “Flatbush diabetes,” type 1.5 diabetes, and more recently, ketosis-prone type 2 diabetes.
Ketosis-prone diabetes, also known as “Flatbush Diabetes”, has pathophysiology close to that of T2DM but initially exhibits signs and symptoms of T1DM . Patients with KPD frequently present with elevated levels of glucose of 500 -700 mg/dL, high levels of ketone, and hemoglobin A 1 C ranging from 12% to 14%.
22 sie 2023 · Ketosis-prone diabetes (KPD) comprises a group of diabetes syndromes characterized by severe beta cell dysfunction (manifested by presentation with DKA or unprovoked ketosis) and a variable clinical course.
The term “Flatbush” Diabetes was first applied to the African Americans residing in the ethnically diverse, Brooklyn, New York neighborhood of Flatbush, who presented in DKA at the time of their diabetes diagnosis. While presenting in DKA, these patients ultimately experience a clinical course resembling type 2 diabetes (T2DM).
Recommendations. Diagnosis of type 1 diabetes should be pursued expeditiously. A pediatric endocrinologist should be consulted before making a diagnosis of type 1 diabetes when isolated glycosuria or hyperglycemia is discovered in the setting of acute illness and in the absence of classic symptoms.
Patients with ketosis-prone type 2 diabetes usually present with new-onset severe hyperglycemia and ketosis or diabetic ketoacidosis. The treatment is the same as diabetic ketoacidosis, which requires insulin, intravenous fluid, and electrolyte replacement.
