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  1. The absence of autoimmunity, lack of beta-cell dysfunction, and unprovoked ketoacidosis are key attributes in KPD, an emerging form of diabetes mellitus [2 - 5]. Interestingly, whether KPD is a unique type or a subtype of type 2 diabetes is still considered a topic of debate and needs further study.

  2. Diabetes mellitus is one of the most common causes of chronic kidney disease. Kidney involvement in patients with diabetes has a wide spectrum of clinical presentations ranging from asymptomatic to overt proteinuria and kidney failure.

  3. 24 sty 2022 · Our report sheds light on the atypicality of presentation and summarizes the main diagnostic features of this rare form of diabetes. Increased awareness of this entity can facilitate early diagnosis and management.

  4. Ketosis-prone diabetes, also known as “Flatbush Diabetes”, has pathophysiology close to that of T2DM but initially exhibits signs and symptoms of T1DM . Patients with KPD frequently present with elevated levels of glucose of 500 -700 mg/dL, high levels of ketone, and hemoglobin A 1 C ranging from 12% to 14%.

  5. Abstract. Diabetic ketoacidosis (DKA) is a triad of uncontrolled hyperglycemia, metabolic acidosis, and increased total body ketone concentration. It is a well-known manifestation of type 1 diabetes mellitus (T1DM). However, it can also be the first presentation of type 2 diabetes mellitus (T2DM).

  6. 2 paź 2018 · KPD is defined as a syndrome in which diabetes commences with ketoacidosis in individuals who are GAD and anti-islet cell antibody negative and have no known precipitating causes. The patients present during middle age, are overweight or mildly obese, and in many reports are more likely to be male.

  7. 1 mar 2022 · Ketone-prone diabetes or Flatbush diabetes is being increasingly recognized worldwide. It is typically seen in obese middle-aged men with a family history of Type 2 DM. Atypicality in the onset of age and gender variation is increasingly observed worldwide.

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