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IN3463/MUM/2011 discloses a process for the preparation of ferric carboxymaltose comprising oxidation of maltodextrin with sodium hypochlorite to provide oxidized maltodextrin followed by...
Background: Ferric carboxymaltose (FCM) formulation consists of iron-carbohydrate nanoparticles where iron-oxyhydroxide as a core is covered by a carbohydrate shell. The present work provides an improved synthesis process of FCM as an intravenous iron, active pharmaceutical ingredient.
14 sty 2021 · Background Ferric carboxymaltose (FCM) formulation consists of iron–carbohydrate nanoparticles that iron– oxyhydroxide as a core is covered by carbohydrate shell. The present work provides an...
Ferric carboxymaltose is an iron complex consisting of a ferric hydroxide core that is stabilized by a carbohydrate shell and allows for controlled delivery of iron to target tissues [51]. The IV administration of ferric carboxymaltose results in transient elevations in serum iron, serum ferritin, and transferrin saturation, and, eventually, in ...
1 lut 2020 · FCM is a polynuclear iron (III)-hydroxide carboxymaltose complex with a molecular weight of ~150,000 Da. It is formulated as a colloidal solution with a near-neutral pH (5.0–7.0) and a physiological osmolarity permitting administration of higher single doses in short time periods.
The intravenous iron formulations ferric carboxymaltose (FCM) and ferric derisomaltose (FDI) offer the possibility of administering a large amount of iron in one infusion. This results in faster correction of anemia and the formulations being better tolerated than oral iron formulations.
Article "An Optimized Process for the Preparation of Aqueous Ferric Carboxymaltose: Synthesis and Structural Characterization" Detailed information of the J-GLOBAL is an information service managed by the Japan Science and Technology Agency (hereinafter referred to as "JST").
