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The main strategies for treating ET currently include the use of oral medications such as β-blockers, antipsychotics, and anticonvulsants. 6 Propranolol, a non-selective β-blocker, is the only drug approved by the U.S. Food and Drug Administration (FDA) for the treatment of ET and is recommended as a first-line treatment in both the AAN ...
Objectives: To conduct an evidence-based review of cur-rent pharmacological and surgical treatments for essential tremor, using standardized criteria defined a priori by the International Parkinson and Movement Disorder Society.
Essential tremor is one of the most common movement disorders in adults and can affect both children and adults. An updated consensus statement in 2018 redefined essential tremor as an isolated action tremor present in bilateral upper extremities for at least three years.
Many treatments for essential tremor have been reported in clinical practice, but it is uncertain which options have the most robust evidence. The International Parkinson and Movement Disorder Society commissioned a task force on tremor to review clinical studies of treatments for essential tremor.
Significant reduction in tremor amplitude in the pregabalin group at a mean dose of 286 mg/day and improvement in action tremor limb scores on the Fahn-Tolosa-Marin (FTM) Tremor Rating Scale (TRS) were observed.
Recently, the Movement Disorders Society (MDS) Task Force on Tremor and the MDS Evidence-Based Medicine Committee reported an evidence-based review of treatments for essential tremor and rated all studies to be classified as having Level-I of clinical evidence for study quality using a previously reported checklist of methodological items ...
9 kwi 2024 · The review targeted non-clinical trial studies of adults with ET evaluating propranolol, primidone, gabapentin, and/or topiramate, and reporting at least upper limb tremor efficacy, safety/adverse events, tolerability, and/or treatment patterns.
