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1 lip 2024 · EPA’s draft risk evaluation preliminarily shows that chronic exposure to 1,1-dichloroethane contributes to the unreasonable risk to aquatic species, including invertebrates and algae, from the manufacturing, processing, and disposal of 1,1-dichloroethane.
13 sie 2002 · Under the draft revised guidelines for carcinogen risk assessment (U.S. EPA, 1999), EPA concludes 1,1-DCE exhibits suggestive evidence of carcinogenicity but not sufficient evidence to assess human carcinogenic potential following inhalation exposure in studies in rodents.
Acute: EPA has found 1,1-dichloroethylene to potentially cause adverse liver effects due to acute exposures at levels above the MCL. Drinking water levels which are considered "safe" for short-term exposures: For a 10-kg (22 lb.) child consuming 1 liter of water per day: a one-day exposure of 2 mg/L; upto a 7-year exposure to 1 mg/L.
27 sie 2024 · Toxicological Profile for 1,2-dichloroethane relied on the increase in kidney weight from the same drinking water study within NTP (1991) for their oral intermediate minimal risk level (MRL) for 1,2-dichloroethane (LOAEL = 58 mg/kg/day). ECRAD evaluated the drinking water study within Munson et al. (1982) and NTP (1991) to be “uninformative.”
breakdown of 1,1,1-trichloroethane, tetrachloroethylene, 1,1,2-trichoroethene, and 1,1-dichloroethane (ATSDR, 1994; IARC, 1999; and U.S. EPA, 1985 a, b). The chemical and physical properties of 1,1-DCE (ATSDR, 1994; IARC, 1999) are presented below. CAS name: 1,1-dichloroethene CAS number: 75-35-4 IUPAC name: 1,1-dichloroethylene
contents of this document, 1,1-dichloroethane may be referred to as the acronyms 1,1-DCA and 1,1-DCE. The acronyms 1,2- DCA, 1,2-DCE, and DCE refer to the chemical 1,2-dichloroethane.
EPA has classified ethylidene dichloride as a Group C, possible human carcinogen. Please Note: The main source of information for this fact sheet is the Agency for Toxic Substances and Disease Registry's (ATSDR's) Toxicological Profile for 1,1-Dichloroethane.
