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Eosinophils, sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. [2] Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma.
3 maj 2022 · Eosinophils are bone marrow-derived granulocytes that remain in the bloodstream for a shorter period of time and mostly reside in tissues. The functions of eosinophils are multifaceted, including antigen presentation, the release of peptides, lipids, and cytokine mediators.
28 sty 2018 · Eosinophils in turn jeopardize tissue integrity by disrupting the architecture of the extracellular matrix and by causing direct cellular damage through the release of specific granules content. Eosinophils are also able to interact with intravascular effectors of innate immunity such as platelets.
eosinophil, type of white blood cell (leukocyte) that is characterized histologically by its ability to be stained by acidic dyes (e.g., eosin) and functionally by its role in mediating certain types of allergic reactions. Eosinophils, along with basophils and neutrophils, constitute a group of white blood cells known as granulocytes.
Eosinophil biology. Eosinophils express a range of receptors, e.g. CCR3, the receptor for CCL11, which allow them to respond to a multitude of cytokines, chemokines and lipid mediators. Eosinophils are recruited from the blood into the tissues at sites of inflammation.
21 cze 2023 · Eosinophils are a kind of blood granulocytes that express cytoplasmic granules that contain basic proteins and bind with acidic dyes like “eosin.” They derive from bone marrow, and their production is stimulated by IL-5, IL-3, and GM-CSF. They have a circulating half-life of 4.5 to 8 hours.
28 lut 2018 · Eosinophils are terminally differentiated cells with a short lifespan of one to two weeks. They circulate in the blood for roughly 10 to 18 hours and subsequently exit capillaries into tissues, where over 95% of eosinophils reside.
