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  1. 23 lut 2024 · Adult or late-onset eosinophilic asthma, distinct from early-onset asthma, is characterized by type-2-high eosinophilic airway inflammation that persists even after inhaled corticosteroid treatment [38,39,40]. From its onset, managing its symptoms is challenging, with patients frequently experiencing continued respiratory discomfort and intense ...

  2. 11 kwi 2014 · Eosinophilic asthma is now recognized as an important subphenotype of asthma based on the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be associated with increased asthma severity, atopy, late-onset disease, and steroid refractoriness.

  3. Asthma is typically associated with Th2-mediated eosinophilic airway inflammation, in contrast to neutrophilic inflammation observed commonly in COPD. However, there is increasing evidence that the eosinophil might play an important role in 10–40% of patients with COPD.

  4. 23 lut 2024 · Eosinophilic asthma, a subtype of asthma, involves the accumulation of eosinophils in the airways. These eosinophils release mediators and cytokines, contributing to severe airway inflammation and tissue damage.

  5. 6 paź 2021 · Eosinophilic inflammation is a feature of allergic asthma. Despite mounting evidence showing that chromatin filaments released from neutrophils mediate various diseases, the understanding of...

  6. 1 sie 2024 · This review discusses the pathological and antiviral roles of eosinophils in asthma and exacerbations. We also highlight the significant reduction in asthma exacerbations seen with biologic therapies, even at the height of the respiratory virus season.

  7. 17 kwi 2013 · Eosinophils are circulating granulocytes involved in pathogenesis of asthma. A cascade of processes directed by Th2 cytokine producing T-cells influence the recruitment of eosinophils into the lungs.

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