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Eosinopenia is a condition where the number of eosinophils, a type of white blood cell, in circulating blood is lower than normal. [1] Eosinophils are a type of granulocyte and consequently from the same cellular lineage as neutrophils , basophils , and mast cells .
Eosinopenia is defined as an absolute eosinophil count of less than 0.09 × 10 9 /L and can be difficult to detect because the reference interval is low. Eosinopenia often accompanies other cytopenias in conditions that result in marrow hypoplasia, specifically involving leukocytes.
24 maj 2021 · Our findings suggested that Eosinopenia has a high incidence in sepsis but has no superiority in comparison with conventional biomarkers for diagnosis of sepsis. However, eosinopenia can still be used in clinical diagnosis for sepsis as a simple, convenient, fast and inexpensive biomarker.
16 mar 2021 · Eosinopenia and the diagnosis and prognosis of SARS-CoV-2 infection. There are now numerous reports that document eosinopenia in patients that present with moderate-to-severe COVID-19 [44–52]. Eosinopenia is not an isolated finding in any of these cases and is typically accompanied by reductions in peripheral lymphocyte, platelet, and ...
24 kwi 2008 · We assessed the value of eosinopenia as marker of sepsis by comparing the eosinophil cell count between noninfected patients (negative, SIRS) and infected patients (sepsis, severe sepsis, and septic shock), and between SIRS patients and infected patients on the day of admission to the ICU.
Eosinopenia is defined as a reduction of circulating eosinophils <0.01 × 109 /l. Idiopathic eosinopenia appears to be a very rare event or syndrome. Eosinopenia in acute stress is mediated by adrenal glucocorticosteroids and epinephrine, while in acute inflammatory states it is not dependent upon the endocrine mechanisms.
Eosinopenia typically accompanies acute response to infection and eosinophil count is a rapid and inexpensive test which could be used to differentiate between infective and other causes of the systemic inlammatory response syndrome (SIRS) in critically ill patients.
