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Eosinopenia is a possible laboratory finding in patients who present with COVID-19 and is associated with disease severity, though it is not pathognomonic. [3] One study found that 53% of patients admitted for COVID-19 had eosinopenia at time of admission; in another study of fatal COVID-19 cases, 81% of patients had eosinopenia. [ 8 ]
Eosinopenia is defined as an absolute eosinophil count of less than 0.09 × 10 9 /L and can be difficult to detect because the reference interval is low. Eosinopenia often accompanies other cytopenias in conditions that result in marrow hypoplasia, specifically involving leukocytes.
16 mar 2021 · Eosinophils are circulating and tissue-dwelling leukocytes that have been implicated in allergic respiratory pathology and antiviral host defense. While eosinopenia has been identified as a factor that may facilitate disease diagnosis and determine prognosis, this finding is neither definitive nor pathognomonic for COVID-19.
5 lip 2024 · The key finding of this study was an association between blood eosinopenia (≤50/μL) and an increase in in-hospital mortality, need for mechanical ventilation, risk of sepsis, length of stay in survivors, and reduced time to in-hospital death in a real-world patient cohort.
18 cze 2020 · This finding is particularly useful and helpful for patients triage at the time of an epidemic outbreak when large number of patients with COVID-19 or COVID-19-like symptoms are expecting confirmative nucleic acid tests and/or radiographic examination, while related resources are limited.
24 maj 2021 · Eosinopenia has been identified as a potential biomarker of sepsis in the past decade. However, its clinical application progress is slow and its recognition is low. Recent studies have again focused on the potential association between Eosinopenia and severe infections.
3 mar 2011 · As a cheap test for early identification of critically ill patients at high risk of mortality on admission to ICU, eosinopenia might aid physicians in their initial decisions, and help to identify patients who may require more aggressive diagnostic and therapeutic interventions.
