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factors as being associated or not associated with the risk of endometrial cancer. This information aims to improve understanding of the current state of the evidence relating to risk and protective factors for endometrial cancer.
In this way, the symptoms, risk factors including an increased risk of cancer, diagnosis, prevention, and treatment of this disorder are discussed. Key words: cancer, endometrial disorder, endometriosis, endometriosis induced pain, clinical management, treatment. ABBREVIATIONS:
8 cze 2022 · Risk factors for EC include body mass index (BMI) (with an increased incidence of +21% for BMI 22-27.2, +43% for BMI 27.5-29-5 and +273% for BMI >30), hypertension, hyperinsulinaemia and prolonged exposure to unopposed estrogen (often related to nulliparity and infertility associated with polycystic ovarian syndrome or tamoxifen use). 4,5.
• We present risk factors for endometrial cancer, including genetic predisposition. • We review the diagnostic and metastatic evaluation of women with endometrial cancer. • We describe the surgical management of early and advanced endometrial cancer.
18 gru 2020 · Minimally invasive surgery is the preferred surgical approach, including patients with high-risk endometrial carcinoma (I, A). Any intra-peritoneal tumor spillage, including tumor rupture or morcellation (including in a bag), should be avoided (III, B).
risk of carcinoma among women with nonatypical endometrial hyperplasia (8). Endometrial intraepithelial neoplasia, however, is much more likely to progress to cancer and may be found coexisting with an undiag-nosed endometrioid carcinoma in 30–50% of cases (9, 10).
This ESMO Clinical Practice Guideline provides key recommendations for managing endometrial cancer. The guideline covers clinical and pathological diagnosis, staging and risk assessment, treatment and follow-up.
