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Many factors affect the risk of developing endometrial cancer, including: Obesity. Things that affect hormone levels, like taking estrogen after menopause, birth control pills, or tamoxifen; the number of menstrual cycles (over a lifetime), pregnancy, certain ovarian tumors, and polycystic ovarian syndrome (PCOS) Use of an intrauterine device (IUD)
11 sie 2023 · Factors that increase the risk of endometrial cancer include: Changes in the balance of hormones in the body. The two main hormones the ovaries make are estrogen and progesterone. Changes in the balance of these hormones cause changes in the endometrium.
A comparison of risk factors for type 1 and type 2 endometrial cancer, showing odds ratios with 95% confidence intervals, from the Epidemiology of Endometrial Cancer Consortium. BMI, body mass index; OC, oral contraceptive.
15 mar 2024 · Thus, risk factors include endometrial hyperplasia, reproductive factors (nulliparity, early menarche and late menopause), polycystic ovary syndrome, postmenopausal estrogen therapy, obesity with adult weight gain, and tamoxifen use.
27 mar 2019 · We don't yet know exactly what causes most cases of endometrial cancer, but we do know there are risk factors, like obesity and hormone imbalance, that are strongly linked to this cancer. We know that most endometrial cancer cells have estrogen and/or progesterone receptors on their surfaces.
Endometrial cancer risk is 2.8 times higher in women with polycystic ovary syndrome (PCOS) versus those without the condition, a meta-analysis showed. Endometrial cancer risk is 4.1 times higher in women aged 54 and under (e.g. premenopausal), versus women of a similar age without PCOS.
21 sie 2023 · Endometrial cancer prevention strategies include avoiding risk factors when possible and increasing protective factors that may help prevent cancer. Learn more about known risk and protective factors and approaches to prevent endometrial cancer in this expert-reviewed summary.