Search results
17 lis 2022 · These difficulties in producing functional human thyroid follicles capable of restoring thyroid function in vivo have been partially overcome by using organoids generated from suspensions of...
19 kwi 2021 · The authors used microdissection to isolate E10.5 lung and thyroid progenitor cells and analyzed them using microarrays. The authors identified transcripts specifically expressed in lung vs. thyroid buds, as well as enriched transcripts common to both lineages.
20 kwi 2021 · Thus, treatment of PSC-derived definitive endoderm with noggin or dorsomorphin and SB431542 to inhibit BMP and TGF-β signaling respectively, has resulted in an AFE-like cell population competent to become lung/thyroid progenitors characterized by the expression of genes common to both lineages (35).
21 maj 2017 · The replacement of regenerated thyroid follicular cells (TFCs) is a promising therapeutic strategy for patients with hypothyroidism. Here, we have succeeded ...
5 gru 2022 · Localization of endogenous thyroperoxidase in thyroid follicles acts as an indicator of iodination during the synthesis of the thyroid hormones. Cytochemical staining of C and oxyphil cells serve as diagnostic markers for tumor, teratoma, and cyst formation in the thyroid gland.
1 kwi 2014 · The persistence of follicular heterogeneity in the mature thyroid therefore appears to indicate the existence of an endogenous mechanism, acting independently of classical negative endocrine feedback, that is essential for maintaining the activity of individual follicles under conditions of an essentially constant TSH supply.
18 cze 2014 · Parafollicular C cells on the other hand, derive from the neuroectoderm and synthesize calcitonin. During embryogenesis, the anteroposterior axis of the foregut endoderm is laid out into organ-specific domains that include the primordial thyroid, lung, pancreas, and liver (18, 19).
