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  1. Ambient GABA targets specific GABA A receptors and evokes tonic inhibition of target cells. Tonic endocannabinoid levels regulate transmitter release probability in several brain areas and cell types. Homosynaptic effects and its plasticity. Glu and GABA transmission is involved and undergo homosynaptic plasticity.

  2. The endocannabinoid system is present in neurons, astrocytes, oligodendrocytes, oligodendrocyte precursor cells (OPCs), and microglia. Functional CB 1 receptors are located on the plasma membrane, but also in mitochondria (mtCB 1) of neurons and astrocytes.

  3. 27 cze 2017 · It is possible that CNS function is translated into circulating endocannabinoids through changes in neuronal or endocrine outputs that drive alterations in endocannabinoid synthesis or...

  4. 2 paź 2020 · This study aimed to investigate associations between basal serum concentrations of the endocannabinoids anandamide (AEA) and 2-arachidonylglycerol (2-AG) with brain functional reward processing.

  5. 1 sty 2022 · Considering both the ubiquity of cannabis and cannabinoid use and the essential function of the endocannabinoid system, my objective in this review is to describe several key clinical issues regarding the interaction between cannabis use and endocannabinoid neurobiology.

  6. 11 lip 2022 · Endocannabinoid signalling is considered one of the most important modulatory systems in a whole organism. Research has yielded great insight on the mechanisms that link endocannabinoids and...

  7. The endocannabinoid system (ECS) is a widespread neuromodulatory network involved in the developing central nervous system as well as playing a major role in tuning many cognitive and physiological processes. The ECS is composed of endogenous cannabinoids, cannabinoid receptors, and the enzymes resp ….

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