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The most useful stem cell for tissue engineering and implantation for the treatment of OA are mesenchymal stem cells (MSCs). These are usually restricted to forming only mesodermal specific cell types (adipocytes, osteoblasts, myocytes, and chondrocytes), but several are able to differentiate into other cell varieties.
- Exploring Orthopedic Stem-Cell Approaches for Osteoarthritis Management ...
Adipose-derived mesenchymal stem cells (ADMSCs) have shown...
- Exploring Orthopedic Stem-Cell Approaches for Osteoarthritis Management ...
10 wrz 2024 · This systematic review aims to explore the potential of intra-articular mesenchymal stem cell (MSC) infiltrations as a therapeutic approach for hip OA. Following PRISMA guidelines, a systematic review was conducted, encompassing PubMed, Embase, and Cochrane Library databases.
23 sty 2021 · Studies have demonstrated safety with minimal complications when using platelet rich plasma, hyaluronic acid, or stem cells to treat hip pain caused by osteoarthritis, femoroacetabular impingement syndrome, tendinopathy, or osteonecrosis of the femoral head.
27 lis 2023 · Although other stem-cell types, including human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs), have been used in OA treatment, ADMSCs have demonstrated superior outcomes. By providing a comprehensive overview of the evolving landscape of stem cell therapies for hip and knee OA, this article highlights the potential of ...
14 lis 2021 · “This novel stem cell therapy has demonstrated improved pain and function, and the stem cells decrease the risk of the femoral head from collapsing. That ultimately translates into fewer young patients requiring hip replacements along with subsequent surgeries in their later years.”
14 gru 2019 · In this review, we discuss the biology of chondrogenesis, the stem cell populations that support articular cartilage in health and disease, and future opportunities afforded through the translation of basic articular chondrocyte stem cell biology into new clinical therapies. Significance statement.
27 lis 2023 · Adipose-derived mesenchymal stem cells (ADMSCs) have shown promise in clinical trials for OA treatment, offering potential pain relief and functional improvement. ADMSCs possess advantages such as accessibility and a favorable safety profile, making them a viable option for OA management.