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  1. Smoking is a well-established and important risk factor for cardiovascular disease. Cessation of smoking clearly decreases the chances of a first or subsequent cardiovascular event. Nicotine replacement therapy (NRT) is a proven adjunctive therapy to increase the probability of quitting smoking.

  2. Intravenous nicotine, nicotine nasal spray and nicotine chewing gum all acutely increase heart rate up to 10 to 15 beats/min and increase blood pressure up to 5 to 10 mm Hg, responses similar to the effects of cigarette smoking ([62–64]).

  3. 4 wrz 2019 · In a study comparing the immediate effect of nicotine on cardiovascular parameters, transdermal nicotine patches, nicotine nasal spray and cigarette smoking were all found to increase systolic and diastolic blood pressures as well as heart rate.

  4. 9 wrz 2024 · Long-term health complications from nicotine gum—especially when used for more than six months—may include insulin resistance, gum disease, and dental problems, as well as an increased risk of heart disease, type 2 diabetes, and ulcers.

  5. 1 cze 1997 · Nicotine may contribute to cardiovascular disease, presumably by hemodynamic consequences of sympathetic neural stimulation and systemic catecholamine release. However, there are many potential cardiovascular toxins in cigarette smoke other than nicotine.

  6. 1 lut 1985 · TN increased heart rate and ratings of aversive side effects (e.g., nausea, lightheadedness) in a dose-related manner, and women were more sensitive at higher doses.

  7. 2 kwi 2010 · Nicotine gum and patches have been shown to increase maternal blood pressure and heart rate, as well as fetal heart rate, but to a lesser degree than cigarette smoking (reviewed in Dempsey and Benowitz, 2001).

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