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2 kwi 2023 · Researchers and clinicians are continually searching for new or more effective measures to help battle hair loss. Hair follicles (HFs) undergo a cycle with four stages: growth (anagen), regression (catagen), rest (telogen), and shedding (exogen) (Fig. 1).
Topical ADSC-Exo has been tried successfully in 39 androgenetic alopecia patients demonstrating significant increases in hair density and thickness. No significant adverse reactions associated with exosome treatment have been reported thus far.
Preclinical studies demonstrate clear benefits of exosome therapeutics in regenerative medicine and for hair loss treatment. Clinical trials demonstrate safety of exosome use in medicine, but data showing efficacy and safety of exosome therapy for alopecia are lacking.
1 kwi 2022 · Exosomes, which are extracellular vesicles involved in cell communication, homeostasis, differentiation, and organogenesis, have been shown to play a central role in hair morphogenesis and...
A recent publication comparing the hair counts among all FDA‐approved treatment options ranked them from highest to lowest: finasteride 1 mg daily (18.37 hairs/cm 2), LLLT (17.66 hairs/cm 2), 5% minoxidil twice daily (14.94 hairs/cm 2), and 2% minoxidil twice daily (8.11 hairs/cm 2). 5 These results, however, were based on studies that varied ...