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1 sty 2024 · A skin test reaction to a drug tested in a non-irritative concentration is indicative of a drug allergy and a potentially harmful drug provocation test can be avoided. New knowledge about and better standardization of skin tests have evolved.
Introduction. Allergy skin testing is essential for the correct diagnosis of immediate and delayed drug hypersensitivity (DH). It is also used to identify alternative drugs for patients with positive skin or provocation tests with suspected drugs.
Skin tests are useful for platinum salt-related immediate hypersensitivity reactions (moderate/strong) 50, while for other chemotherapeutic drugs, experience is limited and test results often negative (low/weak).
5 lut 2022 · Drug skin tests are useful in the work-up of cutaneous adverse drug reactions (CADRs). They can be used to identify the responsible drug(s), to study cross-reactivity between drugs, and to determine safer alternative drugs.
IDT should only be performed if skin prick testing with the venom/drugs has been performed and found to be negative or to identify cross reacting drugs (eg neuromuscular blocking agents) (1,2,3).
A working party of the European Society of Contact Dermatitis (ESCD) for the study of skin testing in investigating cutaneous adverse drug reactions, has proposed the herein-reported guidelines for performing skin testing in CADR in order to standardize these procedures.
10 lis 2023 · If skin test results are negative, proceed to DC, with flexible protocols depending on presentation and risk (ie, full vs subtherapeutic dose, and multiple-day courses if necessary). Cross-reactivity assessments are also considered here, if deemed necessary.
