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1. www.aafp.org › pubs › afpDrug Dosing Adjustments in Patients with Chronic Kidney Disease -...

   www.aafp.org › pubs › afp

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   15 maj 2007 · Chronic kidney disease affects renal drug elimination and other pharmacokinetic processes involved in drug disposition (e.g., absorption, drug distribution, nonrenal clearance...

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2. www.ncbi.nlm.nih.gov › books › NBK560512Renal Failure Drug Dose Adjustments - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK560512

   27 lip 2024 · Renal disease primarily affects drug dosing in 3 ways: Patient susceptibility: Patients with renal impairment may be more vulnerable to a specific drug effect. Pharmacodynamic change: The effect of a drug may be increased or decreased in patients with renal disease.

3. www.ncbi.nlm.nih.gov › pmc › articlesDrug Therapies Affecting Renal Function: An Overview - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   26 lis 2021 · There is a wide range of side effects due to the multiple mechanisms of injury that drugs can have on the kidney. These side effects vary in severity [ 2 ]. Specifically, the incidence of drug-induced acute kidney injury (AKI) is 60% [ 3 ].

4. www.medicinejournal.co.uk › article › S1357-3039(23)00249-9Prescribing medicines for patients with renal impairment

   www.medicinejournal.co.uk › article › S1357-3039(23)00249-9

   Prescribing medicines for patients with renal impairment. Iain M MacIntyre. Affiliations & Notes. Article Info. Download PDF. Abstract. Renal impairment is common worldwide and poses a significant challenge to safe drug prescribing.

5. www.ajkd.org › article › S0272-6386(21)00625-9Principles of Kidney Pharmacotherapy for the Nephrologist: Core...

   www.ajkd.org › article › S0272-6386(21)00625-9

   16 lip 2021 · Given that over half of all medications used in practice undergo extensive kidney elimination, patients with CKD are most vulnerable to potential drug accumulation and toxicity if drug doses are not adjusted appropriately.

6. www.ajkd.org › article › S0272-6386(20)30724-1NSAIDs in CKD: Are They Safe? - American Journal of Kidney...

   www.ajkd.org › article › S0272-6386(20)30724-1

   29 maj 2020 · Nonsteroidal anti-inflammatory drugs (NSAIDs) have long been regarded as dangerous for use in patients with CKD because of their risk for nephrotoxicity and thus alternative classes of analgesics, including opioids, have become more commonly used for pain control in this population.

7. www.sciencedirect.com › science › articleDrug dosing consideration in patients with acute and chronic...

   www.sciencedirect.com › science › article

   1 gru 2011 · Continuous renal replacement therapy (CRRT) is commonly used to manage hemodynamically unstable AKI patients. Several modes of therapy (convective, diffusive, or both), a variety of filter materials, and different effluent flow rates are used, 111,119 all of which can influence drug removal.