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Often, though, chronic kidney disease has no cure. Treatment usually consists of measures to help control signs and symptoms, reduce complications, and slow progression of the disease. If your kidneys become severely damaged, you might need treatment for end-stage kidney disease.
C hronic kidney disease (CKD), as defined by a reduction in the estimated glomerular filtration rate (GFR), is increasing in the United States, 1 in part because of the greater prevalence of obesity and hypertension 2,3 but in greater part because of improved longevity.
27 lip 2024 · Renal disease primarily affects drug dosing in 3 ways: Patient susceptibility: Patients with renal impairment may be more vulnerable to a specific drug effect. Pharmacodynamic change: The effect of a drug may be increased or decreased in patients with renal disease.
10 paź 2023 · End-stage renal disease usually occurs when kidney function is less than 15% of typical kidney function. As a part of kidney disease staging, your provider also might test whether you have protein in your urine.
6 mar 2023 · He says a new class of drugs, SGLT2 inhibitors, is being called a game changer. The drugs were originally designed to treat diabetes — a main cause of chronic kidney disease. Medicines in the SGLT2 inhibitor class include canagliflozin, dapagliflozin and empagliflozin.
1 lip 2019 · Optimal dosing of medications can be influenced by many factors. These factors are important to consider because the therapeutic effects of drugs are frequently concentration dependent and can even result in toxicity. One factor of great importance is the pharmacokinetics of a medication.
Treatment for chronic kidney disease focuses on slowing the progression of kidney damage, usually by controlling the cause. But, even controlling the cause might not keep kidney damage from progressing. Chronic kidney disease can progress to end-stage kidney failure, which is fatal without artificial filtering (dialysis) or a kidney transplant.
