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Dopamine constitutes about 80% of the catecholamine content in the brain. It is an amine synthesized by removing a carboxyl group from a molecule of its precursor chemical, L-DOPA, which is synthesized in the brain and kidneys. Dopamine is also synthesized in plants and most animals.
28 sty 2024 · Dopamine is a neurotransmitter in the brain associated with pleasure, reward, motivation, and motor control. In psychology, it's linked to feelings of gratification and is implicated in mood disorders, addiction, and certain behaviors when its levels are imbalanced.
1 lip 2021 · The most well-characterized sex hormone-related effects on fluid intake, however, are the anti-dipsogenic and anti-natriorexigenic effects of E2. Given that E2 enhances dopamine signaling, and dopamine increases water intake, how can this be reconciled with the inhibitory effect of E2?
8 sie 2022 · In mammals, dopamine comprises 80% of the catecholamine content in the brain, making it the predominant neurotransmitter of its kind. Dopamine is also one of the oldest neurotransmitters, its function being extraordinarily conserved across nearly all animal species, from roundworms to humans.
Dopamine transporter is a transmembrane protein that removes dopamine from the synaptic cleft before it can escape into the biophase. Dopamine transporter knockout mice exhibit a wide range of deficit in dopaminergic functions and altered dopamine-mediated behavior.
16 lis 2018 · In this review, we summarize the aspects of dopamine as a catecholaminergic neurotransmitter and discuss dopamine signaling pathways elicited through dopamine receptor activation in normal brain function.
