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ELDU. Benzathine penicillin G. Beef cattle and calves. 12,000–40,000 U/kg, IM, q 48 h. Greatly extended withdrawal times for production animals should be anticipated; doses >8,800 U/kg constitute ELDU. Penicillin V. Dogs and cats. 15,000 U/kg or 8–10 mg/kg, PO, q 6–8 h. Dicloxacillin sodium monohydrate.
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Tables - Dosages of Penicillins - Merck Veterinary Manual
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In this guide, we will go over the different types of medication for sheep, important medications to have on hand for sheep, and dosage charts for sheep antibiotics and other commonly used medications. Remember, always consult with a veterinarian before making decisions on medication for your sheep.
Dose rate, and frequency and duration of administration: The registered dose rate for LAP preparations (2 ml/40 kg) contains half the dose of procaine penicillin of the procaine penicillin preparations (7.5 mg/kg) and a 5.75 mg/kg dose of penicillin as the benzathine complex – a total dose of 13.25 mg/kg.
Penicillins, in general, have very short elimination half-lives, which is problematic for time-dependent drugs. For example, ~90% of amoxicillin will be eliminated within 4 hours in dogs, suggesting that an 8-hour dosing interval is appropriate.
In order to minimise antibiotic use whilst ensuring the highest standards of sheep welfare, particular emphasis should be made of available preventative strategies for each farm including vaccination, flock security and hygiene measures. Responsible use of antibiotics for treatment of lame sheep should always be practised. To
Protecting sheep health and preserving antimicrobials. Animal Medicines Australia (AMA) continues to support the responsible use of antimicrobial veterinary medicines with the recent development of prescribing guidelines for veterinarians working with the sheep industry.
Veterinarians commonly recommend doses of 3-5ml/100 pounds of bodyweight once or twice a day to achieve therapeutic dosing levels. This deviation from the FDA labeled dose is termed extra-label-drug-use (ELDU).
