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  1. ELDU. Benzathine penicillin G. Beef cattle and calves. 12,000–40,000 U/kg, IM, q 48 h. Greatly extended withdrawal times for production animals should be anticipated; doses >8,800 U/kg constitute ELDU. Penicillin V. Dogs and cats. 15,000 U/kg or 8–10 mg/kg, PO, q 6–8 h. Dicloxacillin sodium monohydrate.

    • Tables

      Tables - Dosages of Penicillins - Merck Veterinary Manual

  2. Penicillins, in general, have very short elimination half-lives, which is problematic for time-dependent drugs. For example, ~90% of amoxicillin will be eliminated within 4 hours in dogs, suggesting that an 8-hour dosing interval is appropriate.

  3. In this guide, we will go over the different types of medication for sheep, important medications to have on hand for sheep, and dosage charts for sheep antibiotics and other commonly used medications. Remember, always consult with a veterinarian before making decisions on medication for your sheep.

  4. Dose rate, and frequency and duration of administration: The registered dose rate for LAP preparations (2 ml/40 kg) contains half the dose of procaine penicillin of the procaine penicillin preparations (7.5 mg/kg) and a 5.75 mg/kg dose of penicillin as the benzathine complex – a total dose of 13.25 mg/kg.

  5. Indications. For the treatment of infections caused by bacteria sensitive to penicillin, where long-acting therapy is required, in horses, cattle, sheep, pigs, dogs and cats. Dosage. 15,000 IU (15 mg)/kg penicillin G procaine with 15,000 IU (11.25 mg)/kg penicillin G benzathine (30,000 IU penicillin per kg body weight) (1 mL/10 kg).

  6. Successful antibiotic treatment is based on 4 principles: 1) identifying the disease-causing agent and selecting the appropriate drug for treatment; 2) attaining effective concentrations of the drug at the site of infection for a sufficient period of time; 3) choosing a dose rate, frequency, and method of administering the dose that maximizes ...

  7. “Research leading to the development of the sheep guidelines found the most common conditions veterinarians prescribed antimicrobial treatments for included kerato-conjunctivitis, foot abscess, pneumonia, virulent ovine footrot and dermatophilosis.

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