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Modeling the Structure of DNA. OVERVIEW. In this activity, students build a paper model of DNA and use their model to explore key structural features of the DNA double helix.
DNA Model. ESTIMATED LENGTH: 85-115 MIN* . In this small group activity, MIDDLE SCHOOL students will make an edible model of a DNA double helix. ugar-phosphate backbone. As students put together their DNA model, they will learn about the base pairing rules and how DNA encodes each organism.
Build a Paper Model of DNA. Fill in the names of the bases on the model shown to the right, or use the detailed model that shows all the atoms in each nucleotide (back side of paper). Cut out the model. Fold all long creases first.
Using the small symbols (squares, circles and stars) on the structures as guides, line up the bases, phosphates and sugars. Glue the appropriate pairs together to form nucleotides. Construct the right side of your DNA molecule by putting together in sequence a cytosine, thymine, guanine and adenine nucleotide.
• Build a model DNA strand. • Analyze the model to see what each of the components represents. • Analyze the model to see what properties of actual DNA are not represented
Origami DNA model. Adapted from Yen, T., 1995, Make your own DNA. Trends in Biochemical Sciences, 20: 94. Folds for your DNA model. Mountain fold. Solid lines are “mountains” and are to be folded away from you with the peak pointing towards you. Making your DNA model. 1. Fold all solid lines going lengthwise down the page into "mountain folds".
In this activity, you will build your own model to understand how DNA works. DNA is a simple molecule made up of four types of chemical building blocks called nucleotides: adenine (A), thymine (T), cytosine (C), and guanine