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DNA ligase is a type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV) may specifically repair double-strand breaks (i.e. a break in both complementary ...
3 sie 2023 · DNA ligase is an enzyme that catalyzes the ligation reaction, ligation is the process of joining various types of DNA fragments. DNA ligase joins the DNA molecule covalently by catalyzing the formation of phosphodiester bonds between adjacent nucleotides.
24 paź 2024 · DNA ligase is an essential enzyme that plays a critical role in the integrity and maintenance of DNA within living organisms. Its primary function is to facilitate the joining of DNA strands by catalyzing the formation of phosphodiester bonds, a crucial process in DNA repair, replication, and recombination.
DNA ligase catalyzes a strand-joining reaction at a nick junction formed by the annealing of two DNA strands on a DNA template. The requirement of base-pair complementarity at the nick junction has been explored to develop ligase-based technologies for the detection of sequence variance.
DNA ligases are essential enzymes that catalyze the joining of DNA strands together by forming phosphodiester bonds, thus sealing nicks or breaks in the DNA backbone. These enzymes play a crucial role in various cellular processes, including DNA replication, repair, and recombination, ensuring the integrity and stability of the genetic material.
DNA ligase is an enzyme that plays a crucial role in maintaining the structural integrity of the genome by repairing breaks in the DNA backbone. It catalyzes the formation of a bond between adjacent nucleotides in the DNA, ensuring the stability of genetic information.
DNA ligases play an essential role in DNA replication, repair, and recombination and are classified as ATP-dependent or NAD-dependent based on their adenylation cofactor requirement. ATP-dependent ligases have been found in bacteriophages, viruses, archaea, eukaryotes and bacteria.
