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8 paź 2024 · Digoxin toxicity ECG changes with dysrhythmias. Review of EKG features of digoxin toxicity and cardiotoxicity with example EKG
- Ed Burns and Robert Buttner
Emergency Physician in Prehospital and Retrieval Medicine in...
- Digoxin Toxicity
Digoxin toxicity is characterised by gastrointestinal...
- Ed Burns and Robert Buttner
Digoxin toxicity is characterised by gastrointestinal distress, hyperkalemia and life-threatening dysryhthmias, including increased automaticity and AV nodal blockade. Digoxin has a narrow therapeutic index and chronic toxicity is more likely in the elderly and those with renal impairment.
8 paź 2024 · The ECG features of digoxin effect are seen with therapeutic doses of digoxin and are due to: Shortening of the atrial and ventricular refractory periods — producing a short QT interval with secondary repolarisation abnormalities affecting the ST segments, T waves and U waves.
4 mar 2023 · Epidemiology. Approximately 1% of patients with heart failure treated with digoxin develop toxicity. Additionally, 1% of adverse drug effects in patients greater than age 40 are due to digoxin toxicity; the incidence rises to greater than 3% in patients over age 85.
17 kwi 2009 · George A. Stouffer MD. Henry A. Foscue Distinguished Professor of Medicine, University of North Carolina, Chapel Hill, NC, USA. Search for more papers by this author
1 lut 2016 · Article. Authors. Subscribe to. Australian Prescriber. SUMMARY. Digoxin toxicity can emerge during long-term therapy as well as after an overdose. It can occur even when the serum digoxin concentration is within the therapeutic range. Toxicity causes anorexia, nausea, vomiting and neurological symptoms. It can also trigger fatal arrhythmias.
The diagnosis of digoxin toxicity is based primarily on clinical suspicion and clinical features (including ECG changes) suggestive of digoxin intoxication, and can be confirmed by assessment of serum digoxin levels.
