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  1. As opposed to the arrhythmias secondary to digoxin toxicity, therapeutic levels of digoxin cause ECG changes known as the ‘digoxin effect’, as seen in Case 1. This simply indicates that the patient is on digoxin and is not a marker of toxicity.

  2. 10 wrz 2024 · While there has been a decline in the use of digoxin in patients with heart failure and atrial fibrillation, acute and chronic digoxin toxicity remains a significant clinical problem.

  3. 19 maj 2024 · At therapeutic levels, digoxin can cause effects on the electrocardiogram, which must be differentiated from digoxin toxicity (see below). The optimal serum concentration of digoxin is 0.5 ng/ml to 1.0 ng/ml.

  4. Digoxin effects on rhythm and conduction. This article concerns adverse side effects of digoxin treatment, with emphasis on ECG changes, arrhythmias and conduction disturbances. Digoxin may cause all known cardiac arrhythmias.

  5. 8 sie 2024 · At therapeutic digoxin concentrations (0.6 to 1.2 nanomol/L [0.5 to 0.9 nanograms/mL]), ECG may show PR-interval prolongation and a scooped ST segment. With toxicity, ECG may show signs of increased automaticity (premature ventricular contractions), atrioventricular nodal blockade, and slowed ventricular response.

  6. 8 paź 2024 · ECG Features of Digoxin Toxicity. The classic digoxin toxic dysrhythmia combines: Supraventricular tachycardia (due to increased automaticity) Slow ventricular response (due to decreased AV conduction) Other common dysrhythmias associated with digoxin toxicity include:

  7. 8 paź 2024 · The ECG features of digoxin effect are seen with therapeutic doses of digoxin and are due to: Shortening of the atrial and ventricular refractory periods — producing a short QT interval with secondary repolarisation abnormalities affecting the ST segments, T waves and U waves.

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