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The diagnosis of digoxin toxicity is based primarily on clinical suspicion and clinical features (including ECG changes) suggestive of digoxin intoxication, and can be confirmed by assessment of serum digoxin levels.
8 sie 2024 · Digoxin toxicity is a clinical diagnosis that relies in part on ECG findings such as signs of increased automaticity and atrioventricular node blockade (premature ventricular contractions, slowed ventricular response), but also on clinical features, history of digoxin intake, history of other illnesses, and elevated digoxin concentrations.
8 paź 2024 · The ECG features of digoxin effect are seen with therapeutic doses of digoxin and are due to: Shortening of the atrial and ventricular refractory periods — producing a short QT interval with secondary repolarisation abnormalities affecting the ST segments, T waves and U waves.
4 mar 2023 · Digoxin's effect on the ECG is characterized by diffuse scooping of the ST segments, which can be seen with therapeutic levels and is not associated with toxicity. The most common ECG abnormality is frequent PVCs, although the "pathognomonic" ECG finding is bidirectional ventricular tachycardia.
Early Recognition of Digoxin Toxicity May Result in Improved Treatment Outcomes 1,2 INDICATION DIGIFab is indicated for the treatment of known (or strongly suspected) life-threatening digoxin toxicity associated with ventricular arrhythmias or
27 lut 2008 · Therefore, the benefits of digoxin can be obtained by maintaining the SDC between 0.5 and 0.9 while minimizing adverse effects and consequences. For HF, therapy with digoxin is commonly initiated and maintained at an oral dose of 0.125 to 0.25 mg daily.
ECG showed sagging ST segment, biphasic T wave and atrial fibrillation with slow ventricular response. Laboratory/imaging work ups, including cerebrospinal fluid analysis, were unrevealing. Digoxin level was checked, showing 2.2 ng/ml.
