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  1. Oral Digoxin Dosage in Children*. * All doses are based on ideal body weight for children with normal renal function. The IV dose is 75% of the oral dose. † A digitalizing dose is now used infrequently.

  2. Use of digoxin is not recommended for treatment of HFpEF in children, unless there is an additional indication such as arrhythmia requiring atrial rate control.

  3. ‡ The initial maintenance dose is 25% of the digitalizing dose, given in 2 divided doses. Adjust dose based on clinical response and drug levels. § Not to exceed adult oral digitalizing dose of 1–1.5 mg.

  4. Treatment with digoxin in infants and children. A digoxin loading oral dose of 25 μg/kg in term infants (aged <1 month) and 35 μg/kg in children (aged 1 month to 2 years) should be followed by a maintenance dose of 10 μg/kg once-daily in infants and a maintenance dose of 15 to 25 μg/kg daily in children [47].

  5. 21 sie 2023 · The initiation of digoxin therapy has been divided into rapid and slow digitalization followed by the maintenance digoxin dose, and the proposed regimens vary considerably. The following principles should be viewed as a general guide to the use of digoxin for its inotropic or electrophysiologic effects, which must be modified according to ...

  6. * All doses are based on ideal body weight for children with normal renal function. The IV dose is 75% of the oral dose. † A digitalizing dose is now used infrequently.

  7. The total digitalizing dose is usually given over 24 hours with half of the dose given initially, followed by one fourth of the dose given twice, separated by 8- to 12-hour intervals; ECG monitoring is necessary. ‡ The maintenance dose is 25% of the digitalizing dose, given in 2 divided doses.

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