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22 kwi 2024 · Grading of diffuse axonal injury due to trauma is described according to the anatomic distribution of injury. Contrary to the implication of the word "diffuse," diffuse axonal injury has a topological predilection for focal involvement of certain sites in the brain.
27 lip 2021 · Diffuse Axonal Injury (DAI) is considered one of the most common and detrimental forms of traumatic brain injury (TBI). The resistant inertia that occurs to the brain at the time of injury, preceding and following its sudden acceleration against the solid skull, causes shearing of the axonal tracts of the white matter.
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22 lip 2024 · Diffuse axonal injury is characterized by multiple focal lesions with a characteristic distribution: typically located at the grey-white matter junction, in the corpus callosum, and in more severe cases in the brainstem (see: grading of diffuse axonal injury).
12 cze 2023 · Grade 1: A mild diffuse axonal injury with microscopic white matter changes in the cerebral cortex, corpus callosum, and brainstem Grade 2: A moderate diffuse axonal injury with gross focal lesions in the corpus callosum
In grade 1 there is histological evidence of axonal injury in the white matter of the cerebral hemispheres, the corpus callosum, the brain stem and, less commonly, the cerebellum. In grade 2 there is also a focal lesion in the corpus callosum.
DAI is classified into grades based on severity of the injury. In Grade I, widespread axonal damage is present but no focal abnormalities are seen. In Grade II, damage found in Grade I is present in addition to focal abnormalities, especially in the corpus callosum.
