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  1. Dietylokarbamazyna (łac. diethylcarbamazinum) – wielofunkcyjny organiczny związek chemiczny, pochodna piperazyny, stosowana jako ogólnoustrojowy lek przeciwrobaczy. Mechanizm działania dietylokarbamazyny nie jest znany, wiadomo jednak, że wpływa na szlak kwasu arachidonowego [5]. Zastosowanie.

  2. 13 cze 2005 · The mechanism of action of diethylcarbamazine is thought to involve sensitizing the microfilariae to phagocytosis. One study showed that diethylcarbamazine's activity against Brugia malayi microfilariae is dependent on inducible nitric-oxide synthase and the cyclooxygenase pathway.

  3. Diethylcarbamazine (DEC) is effective against filariasis, tropical pulmonary eosinophilia, and some forms of asthma. However, no studies have established its mechanism of action on eosinophil accumulation using animal models of allergic inflammation.

  4. 28 lip 2020 · Communications Biology - Verma et al. describe a new mechanism for diethylcarbamazine action, a drug classically used to treat lymphatic filariasis and loiasis. They propose that it induces...

  5. The mechanism of action of diethylcarbamazine is thought to involve sensitizing the microfilariae to phagocytosis. One study showed that diethylcarbamazine's activity against Brugia malayi microfilariae is dependent on inducible nitric-oxide synthase and the cyclooxygenase pathway.

  6. Diethylcarbamazine is a medication used in the treatment of filariasis including lymphatic filariasis, tropical pulmonary eosinophilia, and loiasis. [1] It may also be used for prevention of loiasis in those at high risk. [1]

  7. 9 gru 2022 · Diethylcarbamazine (DEC) is used to treat lymphatic filariasis and activates TRP-2, GON-2 & CED-11 TRP channels in Brugia malayi muscle cells producing spastic paralysis. DEC also has stimulatory...

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