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26 kwi 2021 · Langerhans cells are members of the dendritic cell family and function as antigen-presenting cells (APCs) in the skin. They capture any pathogens they find roaming the epidermis and display their antigens on their surface to stimulate other immune cells into action.
Langerin is a protein found in Langerhans cells, [9] and dendritic cells. [10] LCs contain a large amount of cannabinoid receptor type 2 (CB2), that by activation by agonists, attenuate both the recruitment of eosinophils and ear swelling in chronic contact dermatitis induced by repeated challenge. [11]
Langerhans cells (LCs) are a specialized subset of dendritic cells (DCs) that populate the epidermal layer of the skin. Langerin is a lectin that serves as a valuable marker for LCs in mice...
23 maj 2014 · XC-chemokine receptor 1 (XCR1) + CD11b − conventional dendritic cells (cDCs), CD11b + cDCs, Langerhans cells (LCs), monocyte-derived DCs and macrophages can be readily distinguished on the...
Langerhans cells (LCs) reside in the epidermis as a dense network of immune system sentinels. These cells determine the appropriate adaptive immune response (inflammation or tolerance) by interpreting the microenvironmental context in which they encounter foreign substances.
15 lip 2017 · Our assumptions on the identity and functions of Langerhans cells (LCs) of the epidermis have undergone considerable changes. Once thought to be prototypic representatives of the dendritic cell (DC) lineage, they are now considered to be a specialized subset of tissue-resident macrophages.
19 wrz 2017 · Langerhans cells (LCs) are epidermis-resident antigen-presenting cells that share a common ontogeny with macrophages but function as dendritic cells (DCs). Their development, recruitment and...
