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In this video, rheumatologist Sharon Dowell, MD, describes the challenge of defining and diagnosing flares, their symptoms, triggers and what to do during a ...
25 kwi 2022 · Learn about lupus, its causes, symptoms, treatments, and how to manage flare-ups in this informative YouTube video.
22 maj 2023 · Bullous systemic lupus erythematosus (BSLE) is a rare manifestation of systemic lupus erythematosus. It has clinical and histological features that may lead to misdiagnosis and delayed treatment of this easily treatable condition.
Oral dapsone is sometimes used for rheumatologic skin diseases. It is most commonly used to treat some forms of cutaneous lupus erythematosus (including bullous lupus), vasculitis, and conditions due to increased neutrophils (neutrophilic dermatoses).
Dapsone is occasionally used in the treatment of the autoimmune bullous diseases, a group of disorders resulting from autoimmunity directed against basement membrane and/or intercellular adhesion molecules on cutaneous and mucosal surfaces. This review will summarize the limited published data evaluating dapsone as a therapy for the AIBD.
What is the treatment for bullous systemic lupus erythematosus? Dapsone, at a dose of 1.0–1.5 mg/kg/day, is considered the treatment of choice. It is effective in the vast majority of patients and leads to rapid clinical improvement within days or a few weeks.
Case reports continue to support the use of dapsone for CLE, especially bullous lupus erythematosus. Rituximab and Belimumab have efficacy in patients with systemic lupus erythematosus and severe active CLE.
