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No previous study has described the effects of chronic consumption of the cyclamate and saccharin combination on oxidative stress, lipid profile, glycemic control, creatinine, and alanine transaminase activity in healthy individuals and in patients with type 2 diabetes mellitus (T2DM).
Cyclamate is an artificial sweetener (code E952) with a high sweetening power; according to numerous studies, in some people it can lead to the formation of a substance (CHA) which, when given in significant doses in animal testing, resulted in testicular damage.
Cyclamate is an artificial sweetener. It is 30–50 times sweeter than sucrose (table sugar), making it the least potent of the commercially used artificial sweeteners. It is often used with other artificial sweeteners, especially saccharin; the mixture of 10 parts cyclamate to 1 part saccharin is common and masks the off-tastes of both ...
19 sie 2024 · Sodium cyclamate is highly soluble in water, with a solubility of about 250 g/L at room temperature, allowing it to blend easily in liquid formulations. Its sweetness profile is often described as clean and free of the aftertaste commonly associated with other artificial sweeteners like saccharin.
1 sty 2000 · The present study evaluated the long-term toxic and carcinogenic effects of sodium cyclamate on three monkey species. Of the 21 monkeys that were started on cyclamate as newborns in 1970, 14 survived until the study was terminated in 1994.
Chromosomal aberrations were not induced in the spermatogonia of mice or Chinese hamsters exposed to sodium cyclamate in drinking-water for 150 days or by gavage for five consecutive days, respectively.
Sodium cyclamate is used as an NNS, and the analogous calcium salt is used especially in low-sodium diets. Cyclamate is 30 times sweeter than sucrose. It has a bitter aftertaste but has good sweetness synergy with saccharin. It is soluble in water and its solubility can be increased by preparing the sodium or calcium salt.
