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15 lut 2019 · Cyclamate is an artificial sweetener which may be harmful to human health. Cyclamate may have carcinogenic tendencies. Cyclamate is chemically produced, and its components may cause some side effects.
The cyclamate ban was not just another piece of regulation—it was a tectonic shift, a seismic event that shook the industry to its very core. Overnight, companies that had built their dreams on the sweet promises of cyclamates found themselves staring into the abyss.
The evidence that the risk of cancer is increased among users of artificial sweeteners is inconsistent1. Since the positive report of Howe et al.2, reports have become available on six case-control studies and on one population study of bladder cancer.
The effects of sodium cyclamate on the development of frog embryos were evaluated in a validation study in seven laboratories. The median lethal concentration, the concentration that induced malformations in 50% of the surviving embryos and the teratogenic index, i.e. the ratio of the two other measures, were 16 mg/mL, 14 mg/mL and 1.1 mg/mL ...
Sodium cyclamate is a potent sweetening agent. It has been subjected to numerous safety and carcinogenicity studies. Animal data led to warning against excessive and indiscriminate use a long time ago, causing the World Health Organization in 1967 to adopt a safety limit of 50 mg/kg.
1 sty 2000 · The present study evaluated the long-term toxic and carcinogenic effects of sodium cyclamate on three monkey species. Of the 21 monkeys that were started on cyclamate as newborns in 1970, 14 survived until the study was terminated in 1994.
No previous study has described the effects of chronic consumption of the cyclamate and saccharin combination on oxidative stress, lipid profile, glycemic control, creatinine, and alanine transaminase activity in healthy individuals and in patients with type 2 diabetes mellitus (T2DM).
