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The evidence that the risk of cancer is increased among users of artificial sweeteners is inconsistent 1. Since the positive report of Howe et al. 2, reports have become available on six case-control studies and on one population study of bladder cancer.
No previous study has described the effects of chronic consumption of the cyclamate and saccharin combination on oxidative stress, lipid profile, glycemic control, creatinine, and alanine transaminase activity in healthy individuals and in patients with type 2 diabetes mellitus (T2DM).
In a move that stunned the industry and the public alike, the FDA rescinded its approval of cyclamates in 1969, citing concerns over potential health risks. The sweet dream had turned sour, and the cyclamate comet was heading for a crash. TESTED ON RATS
Cyclamate is an artificial sweetener (code E952) with a high sweetening power; according to numerous studies, in some people it can lead to the formation of a substance (CHA) which, when given in significant doses in animal testing, resulted in testicular damage.
Among the tea-drinkers (98 cases and 281 controls), eight patients and 20 controls reported use of cyclamate, yielding a crude odds ratio of 1.2 (95% CI, 0.5–2.7). The groups of tea-drinkers and coffee-drinkers were mutually exclusive.
Regulators weigh in favorably about cyclamate. Use is approved in more than 100 countries, including Europe, Mexico, Australia. The conclusion that cyclamate can be safely consumed has been reached by an increasing number of governments throughout the world.
29 paź 2019 · The cyclamate bandwagon has made farcical progress in the past week … The truth is that cyclamates have been banned because they are easy to ban, and the new evidence provides the slenderest...
