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Cyclamate is an artificial sweetener (code E952) with a high sweetening power; according to numerous studies, in some people it can lead to the formation of a substance (CHA) which, when given in significant doses in animal testing, resulted in testicular damage.
In 1970, following the results of a controversial study in which rats given extremely high doses of cyclamate and other substances developed bladder tumors, cyclamate was banned in the United States from use in food, beverages and drugs.
Although the FDA has stated that a review of all available evidence does not implicate cyclamate as a carcinogen in mice or rats, [8] cyclamate remains banned from food products in the United States. The petition is now held in abeyance, though not actively considered. [9]
Officially, additives in industrial food are considered harmless. So if you eat little of it and are of a robust constitution, you have nothing to worry about. (For allergies, however, a milligram of the wrong thing can be fatal.)
Several low-calorie synthetic sweeteners have recently emerged in the pharmaceutical and food industries, but their health risks due to their side effects restrict their adoption [4,5]. Several previous studies have shown that the use of artificial sweeteners can be hazardous to human health [6,7].
Cyclamate, odorless white crystalline powder that is used as a nonnutritive sweetener. The name usually denotes either calcium cyclamate or sodium cyclamate. Although they commonly are used as sweeteners in foods and beverages, cyclamates are banned in some places because of safety concerns.
3 maj 2010 · All three “first-generation” sweeteners—cyclamate, saccharin, and aspartame—have been linked to negative health effects. Cyclamate, introduced in 1951, was banned in the United States in 1970.
