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20 lip 2005 · Contralateral breast cancer (CBC) is the most common second primary cancer in patients diagnosed with breast cancer. 1 Patients with a history of breast cancer have an increased risk of developing a second primary breast cancer (PBC), with an annual risk of 0.5% to 1% or a cumulative lifetime risk of 2% to 15%. 2 Because breast cancer is the ...
3 lis 2020 · We aimed to assess contralateral breast cancer (CBC) risk in patients with ductal carcinoma in situ (DCIS) compared with invasive breast cancer (BC). Women diagnosed with DCIS (N = 28,003) or...
17 lut 2021 · Estimates of contralateral breast cancer (CBC) risk in the modern treatment era by year of diagnosis and characteristics of the first breast cancer are needed to assess the impact of recent advances in breast cancer treatment and inform clinical decision making.
A cancer in the contralateral breast in a woman with a previous or synchronous breast cancer is typically considered to be an independent primary tumor. Emerging evidence suggests that in a small subset of these cases the second tumor represents a metastasis.
9 sty 2023 · PDF. Abstract. Purpose. To estimate the risk of contralateral breast cancer (CBC) among women with germline pathogenic variants (PVs) in ATM, BRCA1, BRCA2, CHEK2, and PALB2. Methods. The study population included 15,104 prospectively followed women within the CARRIERS study treated with ipsilateral surgery for invasive breast cancer.
The risk of contralateral breast cancer was similar for DCIS and invasive breast cancer patients. Among women with invasive breast cancer, those with ER-positive tumours had a lower 25-year contralateral breast cancer risk than those with ER-negative tumours (9.5 versus 11.2%, P log-rank <0.0001).
26 maj 2021 · We sought to estimate the annual risk and 25-year cumulative risk of contralateral breast cancer among women with stage 0–III unilateral breast cancer.