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1 cze 2024 · Radon gas is associated with an approximate excess lung cancer risk of 10.0 % per 100 Bq m −3. •. Radon has a more pronounced impact on small-cell lung cancer. •. Radon exhibits a sub-multiplicative synergistic effect when combined with smoking. •. Residential radon exposure, influenced by geological, building, and atmospheric conditions. •.
5 lip 2013 · Ionizing radiation emitted during the radioactive decay of radon and its progeny can induce a variety of cytogenetic effects that can be biologically damaging and result in an increased risk of carcinogenesis.
28 gru 2022 · Abstract. After smoking, residential radon is the second risk factor of lung cancer in general population and the first in never-smokers. Previous studies have analyzed radon attributable...
Radon represents the main risk factor of lung cancer in non-smokers and the second one in smoking patients. In Europe, there are several radon-prone areas, but regulatory policies may vary between countries. Radon causes DNA damage and high genomic tumor instability, but its exact carcinogenesis mechanism in lung cancer remains unknown.
24 lut 2020 · The most remarkable finding is that all histological types of lung cancer were associated with residential radon, with varying strengths of association among the major types. Previous pooled analysis of European also confirmed the finding. SCLC had the strongest relationship with residential radon followed by adenocarcinoma.
27 cze 2022 · An association between radon exposure and oncogenic NSCLC in non-smokers has been hypothesised. This paper provides a practical, concise and updated review on the implications of indoor radon in lung cancer carcinogenesis, and especially of its potential relation with NSCLC with driver genomic alterations.
Results from the meta-analysis. To quantify the association between residential radon exposure and lung cancer risk, we demonstrated that the aERRs per 100 Bq·m −3 were 0.15 (95% CI 0.06–0.25) for never-smokers, 0.09 (95% CI 0.03–0.16) for ever-smokers and 0.11 (95% CI 0.06–0.17) overall (figure 2).
