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Calamine | Fe2O4Zn | CID 23083748 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Calamine, also known as calamine lotion, is a medication made from powdered calamine mineral that is used to treat mild itchiness. [ 2 ] [ 3 ] Conditions treated include sunburn , insect bites, poison ivy , poison oak , and other mild skin conditions.
Powders promote drying and are especially useful in the intertriginous areas. Lotions are powders suspended in water (e.g. calamine lotion). When these preparations dry, they cool the skin and provide a uniform covering of the suspended agent.
Examples include calamine lotion, ciclopirox lotion, and sodium sulfacetamide lotion. Calamine lotion contains 8% each of zinc oxide and calamine, the latter composed of zinc oxide and a small amount of ferric oxide.
Calamine lotion comes under the category of shake lotions and contains calamine and zinc oxide as active ingredients. In addition, it also contains bentonite, glycerine, sodium citrate, and liquified phenol. This article focuses on calamine lotion and preparations that contain calamine lotion.
Assay— Digest about 1.5 g of freshly ignited Calamine, accurately weighed, with 50.0 mL of 1 N sulfuric acid VS, applying gentle heat until no further solution occurs. Filter the mixture, and wash the residue on the filter with hot water until the last washing is neutral to litmus paper.
Dissolve 2 g in a mixture of 20 mL of water and 5 mL of glacial acetic acid R, filter, and add 0.1 mL of potassium chromate (100 g/l) TS to the filtrate; the solution remains clear for 5 minutes. Acid-insoluble substances. Dissolve 2.0 g in 50 mL of hydrochloric acid (~70 g/l) TS, and filter.
