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13 mar 2023 · The decision to treat cold urticaria syndromes depends primarily on the underlying etiology, severity of response to cold stimulus, and how greatly it affects quality of life, including the frequency of anticipated cold exposure.
Our systematic review included 16 studies, 9 of which met the eligibility criteria for the meta-analysis. We analyzed the effects of treatments on critical temperature thresholds (CTTs) and critical stimulation time thresholds (CSTTs), as well as on rates of complete response and adverse events.
In this review, we discuss the clinical features of the various cold-induced urticaria disorders, address the clinical chal-lenge of classifying and managing the varied presentations of these diseases, and highlight the novel genes and associated molecular mechanisms underlying the disease pathogenesis.
After testing, the allergist diagnosed Veronica with “cold urticaria.”. Essentially, cold urticaria means “cold hives.”. It’s the body’s histamine response to a cold stimulus. We learned that cold air could trigger a reaction. Living in the Midwest where long, harsh winters are common, we knew we’d need a well-thought-out plan for ...
Avoidance of cold exposure is the most effective prophylactic measure. In mild to moderate cases, the primary goal of therapy is to improve the patient's quality of life. In more severe cases, treatment measures to protect the patient's airway, breathing, and circulation may be necessary.
This updated version of the international guideline for urticaria covers the definition and classification of urticaria and outlines expert-guided and evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria.
Cold urticaria is a hypersensitivity to cold exposure (eg, wind, freezer compartments, cold water) resulting in histamine release. It usually presents as localized redness, burning, pruritus, and urticaria in the exposed areas, but may progress to a generalized systemic reaction, shock, and death.
